Meaning of sporadic. In the genetic context, sporadic … Denoting a temporal pattern of disease occurrence in an animal or human population in which the disease occurs only rarely and without regularity. Sporadic disease: See also: Sporadic Genetic Diseases: »Introduction: Sporadic Genetic Diseases »Symptoms of Sporadic Genetic Diseases adjective Sporadic occurrences of something happen at irregular intervals....a year of sporadic fighting over northern France. An epidemic (from Greek ἐπί epi "upon or above" and δῆμος demos "people") is the rapid spread of disease to a large number of people in a given population within a short period of time. A widespread disease that affects many individuals in a population. Hyperendemic refers to persistent, high levels of disease occurrence. sporadic (comparative more sporadic, superlative most sporadic) 1. (epidemiology) An occurrence of a disease or disorder in a population at a frequency higher than that expected in a given time period. This assumption cannot be tested, but other comparisons can assess its veracity. There are eight different diseases that affect mammals that are caused by prions such as scrapie, bovine spongiform encephalopathy (mad cow disease) and Feline spongiform encephalopathy (FSE). 2. Hereditary nonpolyposis colorectal cancer (Lynch syndrome or HNPCC), an autosomal dominant disorder, is a disease in families where multiple members have colorectal and other forms of cancer. 2. Information and translations of sporadic in the most comprehensive dictionary definitions resource on … a disease somewhat resembling the Asiatic cholera, but originating where it occurs, and rarely becoming epidemic. The sound of sporadic shooting could still be heard. For example, in meningococcal infections, an attack rate in excess of 15 cases per 100,000 people for two consecutive weeks is considered an epidemic. Credit: Wikipedia Research at the Buck Institute shows the same mechanisms that lead to neuronal cell death in mice genetically fated to develop Parkinson's disease (PD) … Denoting a temporal pattern of disease occurrence in an animal or human population in which the disease occurs only rarely and without regularity. Several quite different and disparate phenomena are covered by this term, including a new mutation; occult nonpaternity; the chance outcome for a recessive trait in two carrier parents with a small family; extreme variability in the expression of a gene; an environmental phenocopy; a multilocal genocopy, etc. appearing in scattered or isolated instances, as a disease. Researchers have identified a mechanism that appears to underlie the common sporadic (non-familial) form of Parkinson’s disease, the progressive movement disorder. Times, Sunday Times (2010) Related word partners sporadic . The sporadic form of the disease, also known as sporadic Creutzfeldt-Jakob disease (CJD), or classical CJD, accounts for approximately 80% of all recognised prion disease. Creutzfeldt–Jakob disease (pronounced KROITS-felt YAH-kohb) or CJD is a neurological disease.It is degenerative (it gets worse over time); it cannot be cured, and it always causes death. a disease which occurs in single and scattered cases. Used of a disease or condition: Most cancers are sporadic, caused by genetic mutations that are not heritable. The majority of cases are sporadic, and usually unilateral. It has been found that prions transmit three ways: obtained, familial, and sporadic. See … In group theory, a sporadic group is one of the 26 exceptional groups found in the classification of finite simple groups.. A simple group is a group G that does not have any normal subgroups except for the trivial group and G itself. For specific diseases, see under the specific name, as addison's disease. All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. Meningitis is an acute inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown. Sporadic disease (Med) a disease which occurs in single and scattered cases. Sporadic CJD occurs in every country with a remarkably similar incidence: approximately one person in … See the Note under Endemic a. Multiple system atrophy (MSA) is a rare neurodegenerative disorder characterized by autonomic dysfunction, tremors, slow movement, muscle rigidity, and postural instability (collectively known as parkinsonism) and ataxia.This is caused by progressive degeneration of neurons in several parts of the brain including the basal ganglia, inferior olivary nucleus, and cerebellum. Sporadic Diseases. CJD is sometimes called a human form of "mad cow disease" (bovine spongiform encephalopathy, or BSE).BSE is actually a cause of one rare type of Creutzfeldt–Jakob disease; the two are not the same disease. In sporadic cases, the misfolding of the prion protein is a process which is hypothesized to occur as a result of the effects of aging on cellular machinery, explaining why the disease often appears later in life. An endemic disease is one which is constantly present in a given area, though usually at low levels, whereas an epidemic is widespread and has a high incidence. Trends of sporadic. It has also been found that plants play the role of vector for prions. Definition of sporadic in the Definitions.net dictionary. See more. 2015 March 12, Daniel Taylor, “Chelsea out of Champions League after Thiago Silva sends 10-man PSG through on away goals”, in The Guardian (London)‎: 2.1.1. Throughout human history, there have been a number of pandemics of diseases such as smallpox and tuberculosis.The most fatal pandemic in recorded history was the Black Death (also known as The Plague), which killed an estimated 75–200 million people in the 14th century. [Medieval Latin sporadicus, scattered, from Greek sporadikos, from sporas, sporad-; see sper- in Indo-European roots.] 2. Sporadic colorectal cancer is the term given to those patients who are affected with the disease, but have no family history of this condition. The term was not used yet but was for later pandemics including the 1918 influenza pandemic (Spanish flu). In the genetic context, sporadic denotes a singleton or sport. It might be outdated or ideologically biased. Cancer that is not due to inherited gene changes is called “sporadic cancer.” It is believed that most- perhaps 90%-of all cancers are sporadic. It was a stodgy, weary display from Mourinho’s team with only sporadicmoments when they threatened Salvatore Sirigu’s goal and their manager seemed bewildered a… An EU study determined that "87% of cases were sporadic, 8% genetic, 5% iatrogenic and less than 1% variant." Endemic refers to the constant presence and/or usual prevalence of a disease or infectious agent in a population within a geographic area. Definition of sporadic : occurring occasionally, singly, or in irregular or random instances sporadic protests a sporadic disease Other Words from sporadic Synonyms & Antonyms Choose the Right Synonym Sporadic Has Medieval Latin Roots More Example Sentences Learn More about sporadic Synonyms & Antonyms for sporadic isolated, as a single instance of something; being or occurring apart from others. occurring singly or … What does sporadic mean? A sporadic disease occurs now and then at low levels. 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